consultancy in computational toxicology

Computational / in silico toxicology is a rapidly developing discipline. If you are looking to incorporate data generated in silico into your safety, hazard or risk assessment, you can choose one of our options.

cosmetic

ingredients

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In Silico Data for Hazard and Safety Assessment 
of Cosmetic Ingredients

Animal testing for the safety assessment of cosmetic ingredients and products has been completely banned in the EU. Consequently the safety assessment of cosmetics requires new methods ...

extractables & 

leachables

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More details soon

plant protection products

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Non-testing methods for Dietary Risk Assessment of Plant Protection Products and their Residues

The Guidance on the establishment of the residue definition for dietary risk assessment adopted by EFSA in 2016  describes a stepwise approach based on toxicological, metabolism and non-testing data ((Q)SAR, read-across and TTC ) ...

drug impurities

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more details soon

REACH

regulation

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Alternatives to testing on animals for the REACH Regulation
(Q)SAR, grouping and read-acros

ECHA says “… We want to encourage registrants to use alternative methods in the best possible way ... The registrants should consider their registration dossiers as “living documents” and regularly update them ” ...

food and

food contact

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more details soon

experience

  • 25 years of experience with in silico  modelling

  • Multiple relevant models are used to increase confidence in the derived toxicity estimates

  • Expert selection of tools and methods in agreement with the official guidelines

  • In silico results complementary to in vitro results

COST EFFECTIVE & FLEXIBLE

  • Free feasibility study

  • In silico methods - lower cost compared to in vitro methods

  • Rapid access to several free and commercial tools

  • Service tailored to your needs (e.g. internal decision making or safety evaluation)

DELIVERY & CUSTOMER SUPPORT

  • Feasibility study typically delivered in two days

  • Study report typically delivered within two weeks

  • 24 hour reactivity to client questions

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ToxNavigation Ltd. is a company registered in England and Wales. Registered number: 11114004. Registered office: Mole View, 158 Bridge Road, East Molesey, Surrey, KT8 9HW.