OECD QSAR Toolbox 4.9 is officially here!

The release of OECD QSAR Toolbox version 4.9 marks a major step forward for chemical risk assessment, bringing fresh datasets, refined metabolic simulators, and seamless data interoperability to your desktop. If you are a toxicologist looking to integrate in silico approaches into your daily hazard identification and data gap filling, this update makes navigating computational workflows easier than ever.

Key Updates in Toolbox 4.9

• Enhanced Interoperability with IUCLID & EFSA: Import toxicokinetics, phototoxicity, and crop/livestock metabolism data directly via OECD Harmonised Templates (OHTs). You also gain direct access to new EFSA public databases containing thousands of documented metabolic maps and metabolites.

• New Prioritization Schemes & Profilers: Take advantage of the Ecotoxicological Risk Classification (ERC) scheme for simplified hazard and ADME prioritization, along with the new MechoA+ profiler for structural alerts predicting mechanisms of toxic action across human and ecotox endpoints.

• Upgraded Profilers & Metabolic Simulators: Enjoy higher accuracy with updated Cramer classification decision trees, refined BfR skin/eye irritation rules, and updated metabolic simulators (including rat liver S9, in vivo rat, and microbial metabolism).

• Smarter Data Workflows: Streamline chemical searching by retrieving data using SMILES notations directly and utilize enhanced workflow tools for metabolite handling and category formation.

Bridge the Computational Gap with ToxNavigation

Transitioning from traditional toxicology to computational methods can feel overwhelming, but you do not have to master it alone. At ToxNavigation, we bridge that gap:

• Tailored Training Courses: We offer flexible on-site, video-streamed, and tutor-assisted eLearning courses designed specifically for toxicologists who want practical, hands-on mastery of tools like QSAR Toolbox 4.9.

• Expert Consultancy: Need rapid, cost-effective risk assessments without the internal steep learning curve? Our expert computational toxicologists can deliver fast, reliable predictions tailored to your regulatory requirements.

Visiting EUROTOX?

Stop by the ToxNavigation booth 81! We would love to answer your computational toxicology questions, and discuss how our training programs can empower your team.