ICH M7 applications for drug impurities and extractables & leachables
Originally, this course was an add-on to our "Use and Applications of QSAR and read-across" course.
However as the core course now provides a good grounding for scientists in silico assessment of mutagenicity and skin sensitisation for drug impurities / extractables and leachables under ICH M7, we have decided to discontinue this module as a standard course.
If you are interested solely in this aspect of computational toxicology, we are pleased to run bespoke courses upon request.
For inquiries, please email: email@example.com
To ensure the quality of the training and to allow all the participants to meet their goals the number of attendees is limited to 20. Registrations will be accepted on a first come, first serve basis.
Session 1 - 2 hours - Searching for chemical data and evaluate structural similarity
Substance, chemical structure, identifiers
Molecular descriptors I
Practical examples will be demonstrated using: ChemSpider, OECD QSAR ToolBox, COSMOS DB, ChemTunes•ToxGPS©, AMBIT
At the end of this session you'll be able to:
Search chemical databases using a identifier, a chemical structure or a chemical substructure
Calculate molecular descriptors
Calculate structural similarity