ICH M7 applications for drug impurities and extractables & leachables
Originally, this course was an add-on to our "Use and Applications of QSAR and read-across" course.
However as the core course now provides a good grounding for scientists in silico assessment of mutagenicity and skin sensitisation for drug impurities / extractables and leachables under ICH M7, we have decided to discontinue this module as a standard course.
If you are interested solely in this aspect of computational toxicology, we are pleased to run bespoke courses upon request.
For inquiries, please email:
To ensure the quality of the training and to allow all the participants to meet their goals the number of attendees is limited to 20. Registrations will be accepted on a first come, first serve basis.
Session 1 - 2 hours - Searching for chemical data and evaluate structural similarity
Substance, chemical structure, identifiers
Molecular descriptors I
Practical examples will be demonstrated using: ChemSpider, OECD QSAR ToolBox, COSMOS DB, ChemTunes•ToxGPS©, AMBIT
At the end of this session you'll be able to:
Search chemical databases using a identifier, a chemical structure or a chemical substructure
Calculate molecular descriptors
Calculate structural similarity