This is the collection of sources on which our training courses on in silico toxicology are built and constantly updated. This list is not intended to be a complete list of publications on computational toxicology, but rather a selection of what we found relevant for our work. The list will be periodically updated, therefore, come back to check the news.

Guidance collection

2021

Guidance collection

NAMs, defined approach, skin sensitization

Guideline No. 497: Defined Approaches on Skin Sensitisation

OECD Guidelines for the Testing of Chemicals, Section 4, OECD Publishing, Paris

2021

Guidance collection

ICH M7, impurities, genotoxicity, QSAR, read-across

ICH M7 Assessment and control of DNA reactive (mutagenic) impurities in pharmaceuticals to limit potential carcinogenic risk

EMA

2021

Guidance collection

EFSA, grouping

Guidance Document on Scientific criteria for grouping chemicals into assessment groups for human risk assessment of combined exposure to multiple chemicals

EFSA

2019

Guidance collection

EFSA, TTC, food

Guidance on the use of the Threshold of Toxicological Concern approach in food safety assessment

EFSA

2018

Guidance collection

ICH M7, impurities, genotoxicity, QSAR, read-across

M7(R1) Assessment and Control of DNA Reactive (Mutagenic) Impurities in Pharmaceuticals To Limit Potential Carcinogenic Risk

FDA

2018

Guidance collection

EFSA, ECHA, endocrine disruptors

Guidance for the identification of endocrine disruptors in the context of Regulations (EU) No 528/2012 and (EC) No 1107/2009

EFSA, ECHA

2017

Guidance collection

read-across, grouping

Guidance on Grouping of Chemicals, Second Edition

OECD

2016

Guidance collection

QSAR, REACH

How to apply ECHA’s practical guide ‘How to use and report (Q)SARs’ for the assessment of substances under BPR

ECHA

2016

Guidance collection

QSAR, REACH

Practical guide How to use and report (Q)SARs

ECHA

2016

Guidance collection

QSAR, read-across, REACH

How to use alternatives to animal testing to fulfil your information requirements for REACH registration

ECHA

2008

Guidance collection

QSAR, read-across, REACH

Guidance on information requirements and chemical safety assessment
Chapter R.6: QSARs and grouping of chemicals

ECHA

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