This is the collection of sources on which our training courses on in silico toxicology are built and constantly updated. This list is not intended to be a complete list of publications on computational toxicology, but rather a selection of what we found relevant for our work. The list will be periodically updated, therefore, come back.

 

In the NAMs Webinar section, you'll find our selection of webinars to keep up to date with the latest developments in the use of New approach methodologies (NAMs) in chemical risk assessment scheduled in the next few months.

Choose a category

Resources

2022

Video collection

PBPK

Gaining acceptance in next generation Physiologically Based Kinetic (PBK) modelling approaches for regulatory assessment: Case studies

OECD, EFSA

2022

Paper collection

Cosmetics, NAMs, read-across, Next generation risk assessment (NGRA)

A 10-Step Framework for Use of Read-across (RAX) in next Generation Risk Assessment (NGRA) for Cosmetics Safety Assessment

Alexander-White, C.; Bury, D.; Cronin, M.; Dent, M.; Hack, E.; Hewitt, N. J.; Kenna, G.; Naciff, J.; Ouedraogo, G.; Schepky, A.; Mahony, C.; Europe, C. Regulatory Toxicology and Pharmacology 2022, 129, 105094.

2022

Video collection

NAMs

Current Concepts in Quantitative Risk Assessment for Skin Sensitization

NICEATM, the Swiss Centre for Applied Human Toxicology, and the Swiss State Secretariat for Economic Affairs.

2022

Paper collection

NAMs, REACH

A framework for chemical safety assessment incorporating new approach methodologies within REACH

Ball, N., Bars, R., Botham, P.A. et al. Arch Toxicol 96, 743–766 (2022).

2022

Tool

QSAR

Danish QSAR models

DTU

2022

Tool

QSAR

VEGA

VEGA-QSAR: AI inside a platform for predictive toxicology, E. Benfenati, A. Manganaro, G. Gini, IRCCS- Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy, DEIB, Politecnico di Milano, Italy

2022

Tool

QSAR

Danish QSAR Database

DTU

2022

Tool

read-across, grouping, trend analysis

OECD QSAR Toolbox

OECD, ECHA, LMS

2022

Video collection

AOP

Building Trust in the Scientific Evidence Base Supporting Chemical Risk Assessment and the Role of the AOP Framework

OECD

2022

Video collection

REACH, read-across, ToolBox

New developments and regulatory applications of the OECD QSAR Toolbox

Andrea Gissi (ECHA), Patience Browne (OECD), Doris Hirmann (ECHA), Darina Yordanova (LMC), Stanislav Temelkov (LMC), Martin B. Philips (US EPA), Brianne Raccor (US EPA), Andrea Richarz (ECHA), Tiago Pedrosa (ECHA)

2022

Video collection

NAMs

Safety assessment of cosmetics and cosmetic ingredients without new animal data

Coordination: AFSA

2022

Paper collection

QSAR, read-across, cosmetics

A Review of In Silico Toxicology Approaches to Support the Safety Assessment of Cosmetics-Related Materials.

Cronin, M. T. D.; Enoch, S. J.; Madden, J. C.; Rathman, J. F.; Richarz, A.-N.; Yang, C. Computational Toxicology 2022, 100213.