A mix between use of commercial and free software tools, consultancy and training on QSAR and read-across.
Regulators are encouraging the use of computational toxicology as a mean of reducing your in vivo and in vitro testing based on existing knowledge. The key issue is to retain the credibility of your chemical risk assessment to the regulator.
The Learn-by-Project concept is a mix between use of commercial and free software tools, consultancy and training on QSAR and read-across. It includes access to ChemTunes·ToxGPS© for the duration of the project and ToxNavigation expertise to work with you and your toxicologist in carrying out the evaluation rather than just give you the answer.
The process can be best described as training with consultancy. The long-term aim is to provide you with the knowledge to conduct your own in silico assessment once you have completed a few projects with ToxNavigation.
The typical Learn-by-Project workflow is outlined below and, if required, can be customized according to your needs. We use a customized version of the workflow described in “Navigating through the minefield of read-across frameworks: A commentary perspective”, Computational Toxicology, Volume 6, May 2018, Pages 39-54, G. Patlewicz, M.T.D. Cronin, G. Helman, J.C. Lambert, L.E. Lizarraga, I. Shah.